Lipids and Lipid Derivatives
Selleck Chemical LLC Glycyrrhizin (NSC 167409) S2302-100mg
Glycyrrhizin (NSC 167409 Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress modulates P38 and P-JNK but not p-ERK signalling Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO)
Apexbio Technology LLC Limonin 1180-71-8 10mM (in 1mL DMSO)
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Cayman Chemical Betulinic acid 500MG
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 100mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Medchemexpress LLC HY-N0892 5mg Medchemexpress, AKBA CAS:67416-61-9 Purity:>98%
Medchemexpress, HY-N0892 5mg AKBA CAS:67416-61-9 AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical GlycyrrhIzIc AcIdamonIum s 5g
A natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions
Medchemexpress LLC Limonin | 1180-71-8 | MFCD00075922 | 99.1% | 470.51 g/mol | C26H30O8 | 10 MG
Limonin (limonoic acid 3,19:16,17 dilactone) is provided as an analytical reference standard intended for research and analytical applications. This small-quantity reference material is used for assay development, method validation, and quantitative analysis where a traceable, high-purity standard is required.
- Analytical reference standard of limonin (limonoic acid 3,19:16,17 dilactone).
- Purity 99.07% as listed on the product page.
- CAS number 1180-71-8.
- Molecular weight 470.51 g/mol.
- Suitable for assay development, quantification, and method validation.
- Available in small package sizes intended for analytical use.
Cayman Chemical 23-hydroxy BetulInIc AcId 25mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 456.7 g/mol | C30H48O3 | 10 MG
Betulinic acid is a natural pentacyclic triterpenoid supplied as an analytical reference for research and chromatographic assays. It is reported to act as a eukaryotic topoisomerase I inhibitor and has documented antiviral, anti-malarial, anti-inflammatory, and antitumor activities.
- Intended for analytical and reference use.
- Natural pentacyclic triterpenoid with reported antiviral and antitumor activity.
- Molecular formula C30H48O3.
- Molecular weight 456.7 g/mol.
- Available as 10 mM in DMSO (1 mL) or as solid reference materials for method development.
- Suitable as a positive control and reference standard in chromatographic assays.
Cayman Chemical GlycyrrhIzIc AcIdamonIum s 25g
A natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions
